Prime Behavior Testing Laboratories Inc. is a US-based company that serves to assist clients with the testing and evaluation of novel therapeutic agents and to identify products that may be suitable for clinical trials in an efficient and cost-effective manner. We specialize in cognition testing (Learning, Memory, and Attention) in rodent and Non-Human Primates (NHPs).
We test the efficacy of novel therapeutics for cognitive and psychiatric disorders. We also test drugs for abuse potential and abuse prevention.
Tests on rodent and Non-Human Primates are overseen by a full-time academic who runs the small animal core facility. We stay current due to ongoing scientific research studies in animal behavior.
PBTLI is unique from most other clinical research organizations - we provide specialized attention and cater our research specifically to your company's needs.
Abstract: Schizophrenia is a devastating mental illness and its effective treatment is among the most challenging issues in psychiatry. The symptoms of schizophrenia are heterogeneous ranging from positive symptoms (e.g., delusions, hallucinations) to negative symptoms (e.g., anhedonia, social withdrawal) to cognitive dysfunction. Antipsychotics are effective at ameliorating positive symptoms in some patients; however, they are not reliably effective at improving the negative symptoms or cognitive impairments. The inability to address the cognitive impairments is a particular concern since they have the greatest long-term impact on functional outcomes....